poilkj wroteYes I installed a second server with tcp openvpn connection. Those clients are useing that new server with tcp protocoll. This is ok.
Good .. that is probably your easiest and most reliable solution.
poilkj wroteThe ISP and connections is a standard coax cable type with standard router. I didnt see "change MTU parameter" there
MTU can rear up anywhere ..
Make sure you are running up-to date openvpn on server and client ..
This may help for the UDP problem:
https://community.openvpn.net/openvpn/wiki/271-i-can-ping-through-the-tunnel-but-any-real-work-causes-it-to-lock-up-is-this-an-mtu-problem
Also, see the manual for MTU related options .. but be careful, you could make things worse. A lot of testing will be required.