Abigail We operate on Azure platform. Our desktop OSes are hosted on cloud. We use Windows 10 on Virtual Desktop on Azure. We need to connect with our business partners through Skype for Business online. Everything was fine until one day, I got error saying, "TLS handshake failed". I use OpenVPN for privacy and security purposes. Is it that the error was caused by some malfunctioning of OpenVPN or due to Skype for business. I need to resolve this issue as soon as possible. Any suggestions to solve this issue would be really helpful. Thanks in advance.