Should be something like;
route 123.45.67.89 255.255.255.255 vpn_gateway
You can put that in the client config file, or, you can put this in the server config file;
push "route 123.45.67.89 255.255.255.255 vpn_gateway"
Check the openvpn documentation. vpn_gateway is a reserved word that translates to the IP of the VPN server in the VPN network.
https://community.openvpn.net/openvpn/wiki/Openvpn23ManPage