this is interesting as i had the same problem connecting with openvpn-gui yesterday on a windows 8.1 machine , which is joined to an active directory domain , regular user account.
i was getting the same error messages
Wed Jul 08 13:35:46 2015 MANAGEMENT: >STATE:1436337346,ADD_ROUTES,,,
Wed Jul 08 13:35:46 2015 C:\Windows\system32\route.exe ADD 202.158.52.202 MASK 255.255.255.255 10.77.0.5
Wed Jul 08 13:35:46 2015 ROUTE: route addition failed using CreateIpForwardEntry: Access is denied. [status=5 if_index=19]
Wed Jul 08 13:35:46 2015 Route addition via IPAPI failed [adaptive]
Wed Jul 08 13:35:46 2015 Route addition fallback to route.exe
Wed Jul 08 13:35:46 2015 env_block: add PATH=C:\Windows\System32;C:\WINDOWS;C:\WINDOWS\System32\Wbem
Wed Jul 08 13:35:46 2015 ERROR: Windows route add command failed [adaptive]: returned error code 1
Wed Jul 08 13:35:46 2015 C:\Windows\system32\route.exe ADD 10.77.0.1 MASK 255.255.255.255 10.77.0.5
Wed Jul 08 13:35:46 2015 ROUTE: route addition failed using CreateIpForwardEntry: Access is denied. [status=5 if_index=19]
Wed Jul 08 13:35:46 2015 Route addition via IPAPI failed [adaptive]
Wed Jul 08 13:35:46 2015 Route addition fallback to route.exe
Wed Jul 08 13:35:46 2015 env_block: add PATH=C:\Windows\System32;C:\WINDOWS;C:\WINDOWS\System32\Wbem
Wed Jul 08 13:35:46 2015 ERROR: Windows route add command failed [adaptive]: returned error code 1
Wed Jul 08 13:35:46 2015 Initialization Sequence Completed
Wed Jul 08 13:35:46 2015 MANAGEMENT: >STATE:1436337346,CONNECTED,SUCCESS,10.77.0.6,54.85.17.249
i could not solve it until i've added the domain user account to the local administrators group on the client computer and run openvpn-gui as administrator with the domain account credentials , but i would rather not do that because now he has privileges to modify other things as well.
so i think i'll give a try to SecurePoint and see what happens , although i think in
Dtravler's case SecurePoint runs by default "As Administrator" and OpenVPN-GUI doesn't , so if your users permissions are not limited like in a Active Directory environment , right clicking on the openvpn-gui's shortcut go to compatibility tab and tick the checkbox "Run as Administrator" will solve your issue.
I don't understand why Cisco's VPN client (IPSec) can set up routes with regular domain user account privileges , but OpenVPN can't.