Yes of course. However your local network and VPN network need to be different subnets. Meaning your local network is 10.10.10.x/24 and your VPN network should be for example 10.8.0.x/24.
After this you make routing between the two networks in 3 steps:
1. In the server configuration file you put a line:
push "route 10.10.10.0 255.255.255.0"
This will make the VPN clients aware of your local network behind the OpenVPN server.
2. Enable IP Forwarding on the openvpn server machine.
This will make your OpenVPN server enable redirecting packets between different networks.
3. In the router on the local network type in a static route to redirect all traffic heading to 10.10.10.x IP addresses to your openvpn server machine (10.10.10.1)
This will enable your machines on the local network to communicate back with the OpenVPN clients.